Modelling the structure of Short Gastrulation and generation of a toolkit for studying its function in Drosophila

Modelling the structure of Short Gastrulation and generation of a toolkit for studying its function in Drosophila

A BMP gradient is essential for patterning the dorsal-ventral axis of invertebrate and vertebrate embryos. The extracellular BMP binding protein Short Gastrulation (Sog) in Drosophila plays a key role in BMP gradient formation. In this study, we combine genome editing, structural and developmental a...

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Bibliographic Details
Main Authors: Sophie L. Frampton, Catherine Sutcliffe, Clair Baldock, Hilary L. Ashe
Format: Article
Language:English
Published: The Company of Biologists 2022-06-01
Series:Biology Open
Subjects:
drosophila
short gastrulation
crispr-cas9
alphafold
model
palmitoylation
Online Access:http://bio.biologists.org/content/11/6/bio059199

Internet

http://bio.biologists.org/content/11/6/bio059199

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