USP5 promotes lipopolysaccharide-induced apoptosis and inflammatory response by stabilizing the TXNIP protein

Background:. The role of thioredoxin-interacting protein (TXNIP) in lipopolysaccharide-induced liver injury in mice has been reported, but the underlying mechanisms are poorly understood. Methods:. We overexpressed deubiquitinase in cells overexpressing TXNIP and then detected the level of TXNIP to...

Full description

Bibliographic Details
Main Authors: Songchang Shi, Xiaobin Pan, Minyong Chen, Lihui Zhang, Shujuan Zhang, Xincai Wang, Songjing Shi, Zhixin Chen, Wei Lin, Yi Jiang
Format: Article
Language:English
Published: Wolters Kluwer Health/LWW 2023-08-01
Series:Hepatology Communications
Online Access:http://journals.lww.com/10.1097/HC9.0000000000000193