Dark-light cycle disrupts bone metabolism and suppresses joint deterioration in osteoarthritic rats

Dark-light cycle disrupts bone metabolism and suppresses joint deterioration in osteoarthritic rats

Abstract Background Light alteration affects the internal environment and metabolic homeostasis of the body through circadian rhythm disorders (CRD). CRD is one of the factors that induce and accelerate osteoarthritis (OA). Therefore, the aim of this study was to evaluate the effects of continuous d...

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Bibliographic Details
Main Authors: Xiaopeng Song, Mingchao Zhao, Jilang Tang, Tianwen Ma, Hui Bai, Xinyu Wang, Lin Liu, Ting Li, Xinyu Xu, Xuanbo Sheng, Binger Zhao, Yingying Wang, Tiantian Wang, Yingchao Guo, Xinmin Zhang, Li Gao
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Arthritis Research & Therapy
Subjects:
Light
Circadian
Osteoarthritis
Rat
Joint
Bone
Online Access:https://doi.org/10.1186/s13075-022-02832-8

Internet

https://doi.org/10.1186/s13075-022-02832-8

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