TIM-3 Suppresses Anti-CD3/CD28-Induced TCR Activation and IL-2 Expression through the NFAT Signaling Pathway.

TIM-3 Suppresses Anti-CD3/CD28-Induced TCR Activation and IL-2 Expression through the NFAT Signaling Pathway.

TIM-3 (T cell immunoglobulin and mucin-domain containing protein 3) is a member of the TIM family of proteins that is preferentially expressed on Th1 polarized CD4+ and CD8+ T cells. Recent studies indicate that TIM-3 serves as a negative regulator of T cell function (i.e. T cell dependent immune re...

সম্পূর্ণ বিবরণ

গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Brian Tomkowicz, Eileen Walsh, Adam Cotty, Raluca Verona, Nina Sabins, Fred Kaplan, Sandy Santulli-Marotto, Chen-Ni Chin, Jill Mooney, Russell B Lingham, Michael Naso, Timothy McCabe
বিন্যাস: প্রবন্ধ
ভাষা:English
প্রকাশিত: Public Library of Science (PLoS) 2015-01-01
মালা:PLoS ONE
অনলাইন ব্যবহার করুন:http://europepmc.org/articles/PMC4619610?pdf=render

আন্তর্জাল

http://europepmc.org/articles/PMC4619610?pdf=render

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