A novel optical microscope for imaging large embryos and tissue volumes with sub-cellular resolution throughout

Current optical microscope objectives of low magnification have low numerical aperture and therefore have too little depth resolution and discrimination to perform well in confocal and nonlinear microscopy. This is a serious limitation in important areas, including the phenotypic screening of human...

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Bibliographic Details
Main Authors: Gail McConnell, Johanna Trägårdh, Rumelo Amor, John Dempster, Es Reid, William Bradshaw Amos
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-09-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/18659