Inhibition of prejunctional parasympathetic pathways by β3-adrenoceptor agonists in the isolated pig detrusor: comparison with human detrusor studies

Inhibition of prejunctional parasympathetic pathways by β3-adrenoceptor agonists in the isolated pig detrusor: comparison with human detrusor studies

Adrenergic receptors of the β3-subtype (β3-ADRs) seem to represent a new target for a more effective pharmacological treatment of overactive bladder (OAB), a wide spread urinary disorder. A promising opportunity for OAB therapy might rely on the development of selective β3-ADR agonists, but an appro...

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Bibliographic Details
Main Authors: Gianluigi D’Agostino, Stefano Salvatore, Paolo Calvi, Anna Maria Condino
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Pharmacology
Subjects:
acetylcholine release
β3-ADR agonist
porcine detrusor
mirabegron
OAB
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1177653/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1177653/full

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