IL-17A promotes tumorigenesis and upregulates PD-L1 expression in non-small cell lung cancer

IL-17A promotes tumorigenesis and upregulates PD-L1 expression in non-small cell lung cancer

Abstract Background The tumor microenvironment plays a key role in non-small cell lung cancer (NSCLC) development and also influences the effective response to immunotherapy. The pro-inflammatory factor interleukin-17A mediates important immune responses in the tumor microenvironment. In this study,...

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Bibliographic Details
Main Authors: Hua Liao, Xiaodan Chang, Lin Gao, Cuiping Ye, Yujie Qiao, Lingyan Xie, Jie Lin, Shaoxi Cai, Hangming Dong
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Journal of Translational Medicine
Subjects:
Interleukin-17A
NSCLC
Autophagy
PD-L1
Immunotherapy
Online Access:https://doi.org/10.1186/s12967-023-04365-3

Internet

https://doi.org/10.1186/s12967-023-04365-3

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