When Hippo meets actin in the nucleus

Nuclear actin is exported from the nucleus via the Exportin-6 (XPO6)/RAN GTPase complex. We recently identified that RASSF1A and the hippo pathway kinase Mammalian STE20-like protein kinase 2 (MST2) play a pivotal role in nucleocytoplasmic shuttling of actin by regulating the association of XPO6 wit...

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Bibliographic Details
Main Authors: Maria Chatzifrangkeskou, Eric O’Neill
Format: Article
Language:English
Published: Taylor & Francis Group 2019-09-01
Series:Molecular & Cellular Oncology
Subjects:
Online Access:http://dx.doi.org/10.1080/23723556.2019.1638728