Retroviruses in the pathogenesis of systemic lupus erythematosus: Are they potential therapeutic targets?

The pathogenesis of systemic lupus erythematosus (SLE) is characterised by the hyper-activation of immunologic pathways related to the antiviral response. Exogenous and endogenous retroviruses, by integrating their DNA templates in the host cell genome, may epigenetically control the transcription o...

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Bibliographic Details
Main Authors: Rossella Talotta, Fabiola Atzeni, Magdalena Janina Laska
Format: Article
Language:English
Published: Taylor & Francis Group 2020-05-01
Series:Autoimmunity
Subjects:
Online Access:http://dx.doi.org/10.1080/08916934.2020.1755962