Exploring the Impact of TREM2 in Tumor-Associated Macrophages

Tumor-associated macrophages (TAMs) represent a key component of the tumor microenvironment and are generally associated with immunosuppression and poor prognosis. TREM2 is a transmembrane receptor of the immunoglobulin superfamily expressed in myeloid cells. TREM2 has been extensively studied in mi...

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Bibliographic Details
Main Authors: Darya Khantakova, Simone Brioschi, Martina Molgora
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/10/6/943