Inflammation-Related Carcinogenesis and Prevention in Esophageal Adenocarcinoma Using Rat Duodenoesophageal Reflux Models

Inflammation-Related Carcinogenesis and Prevention in Esophageal Adenocarcinoma Using Rat Duodenoesophageal Reflux Models

Development from chronic inflammation to Barrett’s adenocarcinoma is known as one of the inflammation-related carcinogenesis routes. Gastroesophageal reflux disease induces regurgitant esophagitis, and esophageal mucosa is usually regenerated by squamous epithelium, but sometimes and somewhere repla...

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Bibliographic Details
Main Authors: Koichi Miwa, Tetsuo Ohta, Takanori Hattori, Koji Nishijima, Tomoharu Miyashita, Shozo Sasaki, Katsunobu Oyama, Takashi Fujimura
Format: Article
Language:English
Published: MDPI AG 2011-08-01
Series:Cancers
Subjects:
inflammation-metaplasia-adenocarcinoma sequence
Barrett’s esophagus
duodenogastroesophageal reflux
chemoprevention for esophageal adenocarcinoma
antireflux surgery
proton pump inhibitors
nonsteroidal anti-inflammatory drugs
selective cyclooxygenase-2 inhibitors
thioproline
Online Access:http://www.mdpi.com/2072-6694/3/3/3206/

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http://www.mdpi.com/2072-6694/3/3/3206/

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