Morphine-induced postconditioning modulates mitochondrial permeability transition pore opening via delta-1 opioid receptors activation in isolated rat hearts

Morphine-induced postconditioning modulates mitochondrial permeability transition pore opening via delta-1 opioid receptors activation in isolated rat hearts

BackgroundIt is generally accepted that morphine affords cardioprotection against ischemia/reperfusion injury. Inhibition of the mitochondrial permeability transition pore (MPTP) is considered an end target for cardioprotection. The aim of this study was to investigate the involvement of opioid rece...

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Bibliographic Details
Main Authors: June Hong Kim, Kook Jin Chun, Yong Hyun Park, Jun Kim, Jeong Su Kim, Young Ho Jang, Mi Young Lee, Jae Hong Park
Format: Article
Language:English
Published: Korean Society of Anesthesiologists 2011-07-01
Series:Korean Journal of Anesthesiology
Subjects:
mitochondrial permeability transition pore
morphine
opioid receptors
postconditioning
reperfusion injury
Online Access:http://ekja.org/upload/pdf/kjae-61-69.pdf

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http://ekja.org/upload/pdf/kjae-61-69.pdf

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