Single cell RNA-seq analysis reveals temporally-regulated and quiescence-regulated gene expression in Drosophila larval neuroblasts

Single cell RNA-seq analysis reveals temporally-regulated and quiescence-regulated gene expression in Drosophila larval neuroblasts

Abstract The mechanisms that generate neural diversity during development remains largely unknown. Here, we use scRNA-seq methodology to discover new features of the Drosophila larval CNS across several key developmental timepoints. We identify multiple progenitor subtypes – both stem cell-like neur...

Full description

Bibliographic Details
Main Authors: Noah Dillon, Ben Cocanougher, Chhavi Sood, Xin Yuan, Andrea B Kohn, Leonid L Moroz, Sarah E Siegrist, Marta Zlatic, Chris Q. Doe
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Neural Development
Subjects:
Neuroblast
Intermediate neural progenitor
Temporal transcription factor
Single cell RNA-sequencing
Quiescence
Insulin signaling
Online Access:https://doi.org/10.1186/s13064-022-00163-7

Internet

https://doi.org/10.1186/s13064-022-00163-7

Similar Items