Structure of herpes simplex virus glycoprotein D bound to the human receptor nectin-1.

Structure of herpes simplex virus glycoprotein D bound to the human receptor nectin-1.

Binding of herpes simplex virus (HSV) glycoprotein D (gD) to a cell surface receptor is required to trigger membrane fusion during entry into host cells. Nectin-1 is a cell adhesion molecule and the main HSV receptor in neurons and epithelial cells. We report the structure of gD bound to nectin-1 de...

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Bibliographic Details
Main Authors: Paolo Di Giovine, Ethan C Settembre, Arjun K Bhargava, Micah A Luftig, Huan Lou, Gary H Cohen, Roselyn J Eisenberg, Claude Krummenacher, Andrea Carfi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-09-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3182920?pdf=render

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http://europepmc.org/articles/PMC3182920?pdf=render

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