Different translation dynamics of β- and γ-actin regulates cell migration

β- and γ-cytoplasmic actins are ubiquitously expressed in every cell type and are nearly identical at the amino acid level but play vastly different roles in vivo. Their essential roles in embryogenesis and mesenchymal cell migration critically depend on the nucleotide sequences of their genes, rath...

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Bibliographic Details
Main Authors: Pavan Vedula, Satoshi Kurosaka, Brittany MacTaggart, Qin Ni, Garegin Papoian, Yi Jiang, Dawei W Dong, Anna Kashina
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-06-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/68712