Kinetics of LYVE-1-positive M2-like macrophages in developing and repairing dental pulp in vivo and their pro-angiogenic activity in vitro

Abstract Tissue-resident macrophages expressing lymphatic vessel endothelial hyaluronan receptor-1 (LYVE-1) are found in multiple tissues and organs. We aimed to evaluate the dynamics and biological functions of LYVE-1+ macrophages in dental pulp during post-injury tissue remodeling. Immunofluoresce...

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Bibliographic Details
Main Authors: Thoai Quoc Kieu, Kento Tazawa, Nobuyuki Kawashima, Sonoko Noda, Mayuko Fujii, Keisuke Nara, Kentaro Hashimoto, Peifeng Han, Takashi Okiji
Format: Article
Language:English
Published: Nature Portfolio 2022-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-08987-3