Phenotypic Assessment of Pathogenic Variants in <i>GNAO1</i> and Response to Caffeine in <i>C. elegans</i> Models of the Disease
De novo mutations affecting the G protein α o subunit (Gαo)-encoding gene (<i>GNAO1</i>) cause childhood-onset developmental delay, hyperkinetic movement disorders, and epilepsy. Recently, we established <i>Caenorhabditis elegans</i> as an informative experimental model for d...
Main Authors: | , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-01-01
|
Series: | Genes |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4425/14/2/319 |