Phenotypic Assessment of Pathogenic Variants in <i>GNAO1</i> and Response to Caffeine in <i>C. elegans</i> Models of the Disease
De novo mutations affecting the G protein α o subunit (Gαo)-encoding gene (<i>GNAO1</i>) cause childhood-onset developmental delay, hyperkinetic movement disorders, and epilepsy. Recently, we established <i>Caenorhabditis elegans</i> as an informative experimental model for d...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-01-01
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| Series: | Genes |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2073-4425/14/2/319 |