Phenotypic Assessment of Pathogenic Variants in <i>GNAO1</i> and Response to Caffeine in <i>C. elegans</i> Models of the Disease
De novo mutations affecting the G protein α o subunit (Gαo)-encoding gene (<i>GNAO1</i>) cause childhood-onset developmental delay, hyperkinetic movement disorders, and epilepsy. Recently, we established <i>Caenorhabditis elegans</i> as an informative experimental model for d...
Main Authors: | Martina Di Rocco, Serena Galosi, Francesca C. Follo, Enrico Lanza, Viola Folli, Alberto Martire, Vincenzo Leuzzi, Simone Martinelli |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-01-01
|
Series: | Genes |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4425/14/2/319 |
Similar Items
-
Vitamin B12 Supplementation Improves Oocyte Development by Modulating Mitochondria and Yolk Protein in a Caffeine-Ingested <i>Caenorhabditis elegans</i> Model
by: Hyemin Min, et al.
Published: (2023-12-01) -
Cognitive Assessment in <i>GNAO1</i> Neurodevelopmental Disorder Using an Eye Tracking System
by: Federica Graziola, et al.
Published: (2021-08-01) -
Genetic Variation in <i>Caenorhabditis elegans</i> Responses to Pathogenic Microbiota
by: Yuqing Huang, et al.
Published: (2020-04-01) -
Improvement of Locomotion Caused by <i>Lactococcus lactis</i> subsp. <i>lactis</i> in the Model Organism <i>Caenorhabditis elegans</i>
by: Mohammad Shaokat Ali, et al.
Published: (2023-10-01) -
Curcumin Acetylsalicylate Extends the Lifespan of <i>Caenorhabditis elegans</i>
by: Lei Zhou, et al.
Published: (2021-10-01)