Expression of transcription factors in MEN1-associated pancreatic neuroendocrine tumors
MEN1-associated pancreatic neuroendocrine tumors (pNETs) may potentially express distinct hormones, but the mechanism has not been elucidated. Transcription factors such as MafA and Pdx1 have been identified to lead to beta cell differentiation, while Arx and Brn4 to alpha cell differentiation in de...
Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Bioscientifica
2017-09-01
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Series: | Endocrinology, Diabetes & Metabolism Case Reports |
Online Access: | https://www.edmcasereports.com/articles/endocrinology-diabetes-and-metabolism-case-reports/10.1530/EDM-17-0088 |