Cytokines regulate the antigen-presenting characteristics of human circulating and tissue-resident intestinal ILCs

Cytokines regulate the antigen-presenting characteristics of human circulating and tissue-resident intestinal ILCs

Murine ILCs can modulate T cell responses in MHCII-dependent manner. Here the authors show that human ILCs process and present antigens and induce T-cell responses upon exposure to IL-1-family cytokines; along with the article by Lehmann et al, this work elucidates how cytokines set context specific...

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Bibliographic Details
Main Authors: Anna Rao, Otto Strauss, Efthymia Kokkinou, Mélanie Bruchard, Kumar P. Tripathi, Heinrich Schlums, Anna Carrasco, Luca Mazzurana, Viktoria Konya, Eduardo J. Villablanca, Niklas K. Björkström, Ulrik Lindforss, Hergen Spits, Jenny Mjösberg
Format: Article
Language:English
Published: Nature Portfolio 2020-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-15695-x

Internet

https://doi.org/10.1038/s41467-020-15695-x

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