Recent developments in application of single-cell RNA sequencing in the tumour immune microenvironment and cancer therapy

Recent developments in application of single-cell RNA sequencing in the tumour immune microenvironment and cancer therapy

Abstract The advent of single-cell RNA sequencing (scRNA-seq) has provided insight into the tumour immune microenvironment (TIME). This review focuses on the application of scRNA-seq in investigation of the TIME. Over time, scRNA-seq methods have evolved, and components of the TIME have been deciphe...

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Bibliographic Details
Main Authors: Pei-Heng Li, Xiang-Yu Kong, Ya-Zhou He, Yi Liu, Xi Peng, Zhi-Hui Li, Heng Xu, Han Luo, Jihwan Park
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Military Medical Research
Subjects:
Single-cell RNA sequencing (scRNA-seq)
Tumour immune microenvironment (TIME)
Trajectory
Cellular interactions
Therapeutic targets
Online Access:https://doi.org/10.1186/s40779-022-00414-y

Internet

https://doi.org/10.1186/s40779-022-00414-y

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