Molecular Basis, Diagnostic Challenges and Therapeutic Approaches of Alport Syndrome: A Primer for Clinicians

Molecular Basis, Diagnostic Challenges and Therapeutic Approaches of Alport Syndrome: A Primer for Clinicians

Alport syndrome is a genetic and hereditary disease, caused by mutations in the type IV collagen genes <i>COL4A3</i>, <i>COL4A4</i> and <i>COL4A5</i>, that affects the glomerular basement membrane of the kidney. It is a rare disease with an underestimated prevalen...

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Bibliographic Details
Main Authors: Raquel Martínez-Pulleiro, María García-Murias, Manuel Fidalgo-Díaz, Miguel Ángel García-González
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:International Journal of Molecular Sciences
Subjects:
Alport syndrome
hereditary kidney disease
chronic kidney disease
collagen
<i>COL4A</i>
Online Access:https://www.mdpi.com/1422-0067/22/20/11063

Internet

https://www.mdpi.com/1422-0067/22/20/11063

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