Cerebral edema in intracerebral hemorrhage: pathogenesis, natural history, and potential treatments from translation to clinical trials

Acute intracerebral hemorrhage is the most devastating stroke subtype and is associated with significant morbidity and mortality. Poor prognosis is associated with primary brain injury from the presenting hematoma, and despite advances in clinical trials of evacuation or reducing expansion, manageme...

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Main Authors: Kailash Krishnan, Paula Bermell Campos, Thanh N. Nguyen, Chia Wei Tan, Siang Liang Chan, Jason P. Appleton, ZheKang Law, Milo Hollingworth, Matthew A. Kirkman, Timothy J. England, Christine Roffe, Mary Joan Macleod, Jesse Dawson, Ulvi Bayraktutan, David J. Werring, Nikola Sprigg, Philip M. Bath
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Stroke
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fstro.2023.1256664/full