Preparation and Preliminary Imaging of Novel Albumin-Binding PSMA Ligand [177Lu]Lu-DOTA-CPN-PSMA

A novel PSMA targeting molecule [177Lu]Lu-DOTA-CPN-PSMA with high uptake and long retention in prostate cancer was developed, in which DOTA was used as the bifunctional chelator, glutamic acid-urea-lysine(Glu-Urea-Lys) was used as the targeting group, and 4-(p-tolyl)butyric acid(CP) group together w...

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Bibliographic Details
Main Authors: LUO Tian-wei, SUN Ming-yue, ZHANG Wen-hui, GAO Fei, WANG Ning, HUANG Xu-hu, CHEN Huan, LI Hong-yu
Format: Article
Language:zho
Published: Editorial Office of Journal of Nuclear and Radiochemistry 2023-12-01
Series:He huaxue yu fangshe huaxue
Subjects:
Online Access:http://www.jnrc.org.cn/CN/10.7538/hhx.2023.45.06.0573