Stereoselective alkoxycarbonylation of unactivated C(sp3)–H bonds with alkyl chloroformates via Pd(II)/Pd(IV) catalysis
Carbonylation of unactivated C-H bonds is typically carried out on primary C-H sites using gaseous carbon monoxide. Here the authors report a palladium cataylsed alkoxycarbonylation process using alkyl chloroformates that functionalises more challenging unactivated secondary C-H sites.
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2016-09-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/ncomms12901 |
| _version_ | 1818717024655769600 |
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| author | Gang Liao Xue-Song Yin Kai Chen Qi Zhang Shuo-Qing Zhang Bing-Feng Shi |
| author_facet | Gang Liao Xue-Song Yin Kai Chen Qi Zhang Shuo-Qing Zhang Bing-Feng Shi |
| author_sort | Gang Liao |
| collection | DOAJ |
| description | Carbonylation of unactivated C-H bonds is typically carried out on primary C-H sites using gaseous carbon monoxide. Here the authors report a palladium cataylsed alkoxycarbonylation process using alkyl chloroformates that functionalises more challenging unactivated secondary C-H sites. |
| first_indexed | 2024-12-17T19:28:35Z |
| format | Article |
| id | doaj.art-e79fad644ab943149229cbef60c494d5 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-17T19:28:35Z |
| publishDate | 2016-09-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-e79fad644ab943149229cbef60c494d52022-12-21T21:35:20ZengNature PortfolioNature Communications2041-17232016-09-01711910.1038/ncomms12901Stereoselective alkoxycarbonylation of unactivated C(sp3)–H bonds with alkyl chloroformates via Pd(II)/Pd(IV) catalysisGang Liao0Xue-Song Yin1Kai Chen2Qi Zhang3Shuo-Qing Zhang4Bing-Feng Shi5Department of Chemistry, Zhejiang UniversityDepartment of Chemistry, Zhejiang UniversityDivision of Chemistry and Chemical Engineering, California Institute of TechnologyDepartment of Chemistry, Zhejiang UniversityDepartment of Chemistry, Zhejiang UniversityDepartment of Chemistry, Zhejiang UniversityCarbonylation of unactivated C-H bonds is typically carried out on primary C-H sites using gaseous carbon monoxide. Here the authors report a palladium cataylsed alkoxycarbonylation process using alkyl chloroformates that functionalises more challenging unactivated secondary C-H sites.https://doi.org/10.1038/ncomms12901 |
| spellingShingle | Gang Liao Xue-Song Yin Kai Chen Qi Zhang Shuo-Qing Zhang Bing-Feng Shi Stereoselective alkoxycarbonylation of unactivated C(sp3)–H bonds with alkyl chloroformates via Pd(II)/Pd(IV) catalysis Nature Communications |
| title | Stereoselective alkoxycarbonylation of unactivated C(sp3)–H bonds with alkyl chloroformates via Pd(II)/Pd(IV) catalysis |
| title_full | Stereoselective alkoxycarbonylation of unactivated C(sp3)–H bonds with alkyl chloroformates via Pd(II)/Pd(IV) catalysis |
| title_fullStr | Stereoselective alkoxycarbonylation of unactivated C(sp3)–H bonds with alkyl chloroformates via Pd(II)/Pd(IV) catalysis |
| title_full_unstemmed | Stereoselective alkoxycarbonylation of unactivated C(sp3)–H bonds with alkyl chloroformates via Pd(II)/Pd(IV) catalysis |
| title_short | Stereoselective alkoxycarbonylation of unactivated C(sp3)–H bonds with alkyl chloroformates via Pd(II)/Pd(IV) catalysis |
| title_sort | stereoselective alkoxycarbonylation of unactivated c sp3 h bonds with alkyl chloroformates via pd ii pd iv catalysis |
| url | https://doi.org/10.1038/ncomms12901 |
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