SAA fibrils involved in AA amyloidosis are similar in bulk and by single particle reconstitution: A MAS solid-state NMR study

SAA fibrils involved in AA amyloidosis are similar in bulk and by single particle reconstitution: A MAS solid-state NMR study

AA amyloidosis is one of the most prevalent forms of systemic amyloidosis and affects both humans and other vertebrates. In this study, we compare MAS solid-state NMR data with a recent cryo-EM study of fibrils involving full-length murine SAA1.1. We address the question whether the specific require...

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Bibliographic Details
Main Authors: Arpita Sundaria, Falk Liberta, Dilan Savran, Riddhiman Sarkar, Natalia Rodina, Carsten Peters, Nadine Schwierz, Christian Haupt, Matthias Schmidt, Bernd Reif
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Journal of Structural Biology: X
Subjects:
Magic Angle Spinning (MAS)
Solid-state NMR
Amyloid fibrils
Structure
Cryo electron microscopy (EM)
Online Access:http://www.sciencedirect.com/science/article/pii/S2590152422000101

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http://www.sciencedirect.com/science/article/pii/S2590152422000101

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