Synthesis of Natural (−)-Antrocin and Its Enantiomer via Stereoselective Aldol Reaction

The total synthesis of (&#8722;)-antrocin and its enantiomer are presented. Antrocin (&#8722;)-<b>1</b> is an important natural product which acts as an antiproliferative agent in a metastatic breast cancer cell line (IC<sub>50</sub>: 0.6 <i>&#956;</i>...

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Bibliographic Details
Main Authors: Venkatachalam Angamuthu, Dar-Fu Tai
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/25/4/831