Target-directed catalytic metallodrugs

Most drugs function by binding reversibly to specific biological targets, and therapeutic effects generally require saturation of these targets. One means of decreasing required drug concentrations is incorporation of reactive metal centers that elicit irreversible modification of tar...

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Bibliographic Details
Main Authors: J.C. Joyner, J.A. Cowan
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2013-07-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013000600465&lng=en&tlng=en