Structure-based design and activity modeling of novel epidermal growth factor receptor kinase inhibitors; an in silico approach
The development of EGFR kinase inhibitors to treat non-small cell lung cancers is an important medical necessity due to persistent development of resistance by the mutations. In-view of this, a model with a very high predictive ability on thirty (30) EGFR kinase inhibitors was built using QSAR molec...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2020-09-01
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| Series: | Scientific African |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2468227620302416 |