iE-DAP Induced Inflammatory Response and Tight Junction Disruption in Bovine Mammary Epithelial Cells via NOD1-Dependent NF-κB and MLCK Signaling Pathway

iE-DAP Induced Inflammatory Response and Tight Junction Disruption in Bovine Mammary Epithelial Cells via NOD1-Dependent NF-κB and MLCK Signaling Pathway

<i>γ</i>-D-glutamyl-<i>meso</i>-diaminopimelic acid (iE-DAP), a bacterial cell wall component, can trigger an inflammatory response. A mammary inflammatory response causes tight junction (TJ) dysfunction. This study aimed to explore the effects and involved mechanisms of iE-D...

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Bibliographic Details
Main Authors: Yan Wang, Xuerui Li, Zhengqiang Han, Meijuan Meng, Xiaoli Shi, Lairong Wang, Mengru Chen, Guangjun Chang, Xiangzhen Shen
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:International Journal of Molecular Sciences
Subjects:
bovine mammary epithelial cell
iE-DAP
inflammatory response
tight junction
NF-κB
Online Access:https://www.mdpi.com/1422-0067/24/7/6263

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https://www.mdpi.com/1422-0067/24/7/6263

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