Low prevalence of CHEK2 gene mutations in multiethnic cohorts of breast cancer patients in Malaysia.

Low prevalence of CHEK2 gene mutations in multiethnic cohorts of breast cancer patients in Malaysia.

CHEK2 is a protein kinase that is involved in cell-cycle checkpoint control after DNA damage. Germline mutations in CHEK2 gene have been associated with increase in breast cancer risk. The aim of this study is to identify the CHEK2 gene germline mutations among high-risk breast cancer patients and i...

Fuld beskrivelse

Bibliografiske detaljer
Main Authors: Suriati Mohamad, Nurismah Md Isa, Rohaizak Muhammad, Nor Aina Emran, Nor Mayah Kitan, Peter Kang, In Nee Kang, Nur Aishah Mohd Taib, Soo Hwang Teo, Sharifah Noor Akmal
Format: Article
Sprog:English
Udgivet: Public Library of Science (PLoS) 2015-01-01
Serier:PLoS ONE
Online adgang:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0117104&type=printable

Internet

https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0117104&type=printable

Lignende værker