Deep nasal sinus cavity microbiota dysbiosis in Parkinson’s disease

Abstract Olfactory dysfunction is a pre-motor symptom of Parkinson’s disease (PD) that appears years prior to diagnosis and can affect quality of life in PD. Changes in microbiota community in deep nasal cavity near the olfactory bulb may trigger the olfactory bulb-mediated neuroinflammatory cascade...

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Bibliographic Details
Main Authors: Gian Pal, Vivian Ramirez, Phillip A. Engen, Ankur Naqib, Christopher B. Forsyth, Stefan J. Green, Mahboobeh Mahdavinia, Pete S. Batra, Bobby A. Tajudeen, Ali Keshavarzian
Format: Article
Language:English
Published: Nature Portfolio 2021-12-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-021-00254-y