Study of <i>Helicobacter pylori</i> Isolated from a High-Gastric-Cancer-Risk Population: Unveiling the Comprehensive Analysis of Virulence-Associated Genes including Secretion Systems, and Genome-Wide Association Study

Study of <i>Helicobacter pylori</i> Isolated from a High-Gastric-Cancer-Risk Population: Unveiling the Comprehensive Analysis of Virulence-Associated Genes including Secretion Systems, and Genome-Wide Association Study

Background: The prevalence of gastric cancer in Mongolia, in East Asia, remains the highest in the world. However, most <i>Helicobacter pylori</i> strains in Mongolia have a less virulent Western-type CagA. We aimed to determine how <i>H. pylori</i> genomic variation affected...

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Bibliographic Details
Main Authors: Batsaikhan Saruuljavkhlan, Ricky Indra Alfaray, Khasag Oyuntsetseg, Boldbaatar Gantuya, Ayush Khangai, Namsrai Renchinsengee, Takashi Matsumoto, Junko Akada, Dashdorj Azzaya, Duger Davaadorj, Yoshio Yamaoka
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Cancers
Subjects:
gastric diseases
virulence factor
<i>cag</i> pathogenicity island
integrative and conjugative element (ICE)
outer membrane proteins
population genomics
Online Access:https://www.mdpi.com/2072-6694/15/18/4528

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https://www.mdpi.com/2072-6694/15/18/4528

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