Released Myeloperoxidase Attenuates Neutrophil Migration and Accumulation in Inflamed Tissue

Released Myeloperoxidase Attenuates Neutrophil Migration and Accumulation in Inflamed Tissue

Neutrophil (PMN) recruitment to sites of insult is critical for host defense, however excessive PMN activity and tissue accumulation can lead to exacerbated inflammation and injury. Myeloperoxidase (MPO) is a PMN azurophilic granule enzyme, which together with H2O2, forms a powerful antimicrobial sy...

Full description

Bibliographic Details
Main Authors: Jacob F. Rehring, Triet M. Bui, Carlos Samuel Galán-Enríquez, Jessica M. Urbanczyk, Xingsheng Ren, Hannah L. Wiesolek, David P. Sullivan, Ronen Sumagin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Immunology
Subjects:
neutrophils
adhesion
migration
inflammation
imaging
myeloperoxidase (MPO)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.654259/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.654259/full

Similar Items