Abnormal outer hair cell efferent innervation in Hoxb1-dependent sensorineural hearing loss.

Autosomal recessive mutation of HOXB1 and Hoxb1 causes sensorineural hearing loss in patients and mice, respectively, characterized by the presence of higher auditory thresholds; however, the origin of the defects along the auditory pathway is still unknown. In this study, we assessed whether the ab...

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Bibliographic Details
Main Authors: Maria Di Bonito, Jérôme Bourien, Monica Tizzano, Anne-Gabrielle Harrus, Jean-Luc Puel, Bice Avallone, Regis Nouvian, Michèle Studer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-09-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1010933