Functional and spatial proteomics profiling reveals intra- and intercellular signaling crosstalk in colorectal cancer

Functional and spatial proteomics profiling reveals intra- and intercellular signaling crosstalk in colorectal cancer

Summary: Precision oncology approaches for patients with colorectal cancer (CRC) continue to lag behind other solid cancers. Functional precision oncology—a strategy that is based on perturbing primary tumor cells from cancer patients—could provide a road forward to personalize treatment. We extend...

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Bibliographic Details
Main Authors: Christina Plattner, Giorgia Lamberti, Peter Blattmann, Alexander Kirchmair, Dietmar Rieder, Zuzana Loncova, Gregor Sturm, Stefan Scheidl, Marieke Ijsselsteijn, Georgios Fotakis, Asma Noureen, Rebecca Lisandrelli, Nina Böck, Niloofar Nemati, Anne Krogsdam, Sophia Daum, Francesca Finotello, Antonios Somarakis, Alexander Schäfer, Doris Wilflingseder, Miguel Gonzalez Acera, Dietmar Öfner, Lukas A. Huber, Hans Clevers, Christoph Becker, Henner F. Farin, Florian R. Greten, Ruedi Aebersold, Noel F.C.C. de Miranda, Zlatko Trajanoski
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:iScience
Subjects:
Cancer systems biology
Cancer
Proteomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223024768

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http://www.sciencedirect.com/science/article/pii/S2589004223024768

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