Innate Immune Defense Mechanisms by Myeloid Cells That Hamper Cancer Immunotherapy

Innate Immune Defense Mechanisms by Myeloid Cells That Hamper Cancer Immunotherapy

Over the past decade, cancer immunotherapy has been steering immune responses toward cancer cell eradication. However, these immunotherapeutic approaches are hampered by the tumor-promoting nature of myeloid cells, including monocytes, macrophages, and neutrophils. Despite the arsenal of defense str...

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Bibliographic Details
Main Authors: Els Lebegge, Sana M. Arnouk, Pauline M. R. Bardet, Máté Kiss, Geert Raes, Jo A. Van Ginderachter
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Immunology
Subjects:
cancer immunotherapy
tumor-associated myeloid cells
tumor microenvironment
innate immune response
immune suppression
immunotherapy resistance
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01395/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.01395/full

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