Repurposing of Nitroxoline as an Alternative Primary Amoebic Meningoencephalitis Treatment

Repurposing of Nitroxoline as an Alternative Primary Amoebic Meningoencephalitis Treatment

Among the pathogenic free-living amoebae (FLA), <i>Naegleria fowleri</i> is the etiological agent of a fatal disease known as primary amoebic meningoencephalitis (PAM). Once infection begins, the lesions generated in the central nervous system (CNS) result in the onset of symptoms leadin...

Full description

Bibliographic Details
Main Authors: Javier Chao-Pellicer, Iñigo Arberas-Jiménez, Frieder Fuchs, Ines Sifaoui, José E. Piñero, Jacob Lorenzo-Morales, Patrick Scheid
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Antibiotics
Subjects:
<i>Naegleria fowleri</i>
primary amoebic meningoencephalitis
drug repurposing
Nitroxoline
programmed cell death
8-hydroxy-quinoline
Online Access:https://www.mdpi.com/2079-6382/12/8/1280

Internet

https://www.mdpi.com/2079-6382/12/8/1280

Similar Items