Impact of <i>TMPRSS2</i> Expression, Mutation Prognostics, and Small Molecule (CD, AD, TQ, and TQFL12) Inhibition on Pan-Cancer Tumors and Susceptibility to SARS-CoV-2

Impact of <i>TMPRSS2</i> Expression, Mutation Prognostics, and Small Molecule (CD, AD, TQ, and TQFL12) Inhibition on Pan-Cancer Tumors and Susceptibility to SARS-CoV-2

As a cellular protease, transmembrane serine protease 2 (TMPRSS2) plays roles in various physiological and pathological processes, including cancer and viral entry, such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Herein, we conducted expression, mutation, and prognostic analyse...

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Bibliographic Details
Main Authors: Jiewen Fu, Shuguang Liu, Qi Tan, Zhiying Liu, Jie Qian, Ting Li, Jiaman Du, Binghui Song, Dabing Li, Lianmei Zhang, Jiayue He, Kan Guo, Baixu Zhou, Hanchun Chen, Shangyi Fu, Xiaoyan Liu, Jingliang Cheng, Tao He, Junjiang Fu
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Molecules
Subjects:
<i>TMPRSS2</i> gene
SARS-CoV-2
prostate adenocarcinoma
susceptibility
cordycepin (CD)
adenosine (AD)
Online Access:https://www.mdpi.com/1420-3049/27/21/7413

Internet

https://www.mdpi.com/1420-3049/27/21/7413

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