NF-κB p65 Attenuates Cardiomyocyte PGC-1α Expression in Hypoxia

NF-κB p65 Attenuates Cardiomyocyte PGC-1α Expression in Hypoxia

Hypoxia exerts broad effects on cardiomyocyte function and viability, ranging from altered metabolism and mitochondrial physiology to apoptotic or necrotic cell death. The transcriptional coactivator peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α) is a key regulator of...

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Bibliographic Details
Main Authors: Inna Rabinovich-Nikitin, Alexandra Blant, Rimpy Dhingra, Lorrie A. Kirshenbaum, Michael P. Czubryt
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Cells
Subjects:
NF-κB
hypoxia
PGC-1α
mitochondria
gene transcription
cardiac myocytes
Online Access:https://www.mdpi.com/2073-4409/11/14/2193

Internet

https://www.mdpi.com/2073-4409/11/14/2193

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