Endoplasmic reticulum stress related genome-wide Mendelian randomization identifies therapeutic genes for ulcerative colitis and Crohn’s disease

Endoplasmic reticulum stress related genome-wide Mendelian randomization identifies therapeutic genes for ulcerative colitis and Crohn’s disease

Background: Endoplasmic reticulum stress (ERS) is an important pathophysiological mechanism in ulcerative colitis (UC) and Crohn’s disease (CD). ERS-related genes may be influenced by genetic factors and intestinal inflammation. However, the role of ERS as a trigger or potential etiological factor f...

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Bibliographic Details
Main Authors: Menglong Zou, Qiaoli Liang, Wei Zhang, Ying Zhu, Yin Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Genetics
Subjects:
summary data-based Mendelian randomization
endoplasmic reticulum stress
ulcerative colitis
Crohn’s disease
integrative omics analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1270085/full

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https://www.frontiersin.org/articles/10.3389/fgene.2023.1270085/full

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