Quantitative properties of the creation and activation of a cell-intrinsic duration-encoding engram

Quantitative properties of the creation and activation of a cell-intrinsic duration-encoding engram

The engram encoding the interval between the conditional stimulus (CS) and the unconditional stimulus (US) in eyeblink conditioning resides within a small population of cerebellar Purkinje cells. CSs activate this engram to produce a pause in the spontaneous firing rate of the cell, which times the...

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Bibliographic Details
Main Authors: Charles Randy Gallistel, Fredrik Johansson, Dan-Anders Jirenhed, Anders Rasmussen, Matthew Ricci, Germund Hesslow
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Computational Neuroscience
Subjects:
Shannon information
timing
cerebellum
classical conditioning
Purkinje cell
reinforcement learning
Online Access:https://www.frontiersin.org/articles/10.3389/fncom.2022.1019812/full

Internet

https://www.frontiersin.org/articles/10.3389/fncom.2022.1019812/full

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