Low temperature-dependent salmonid alphavirus glycoprotein processing and recombinant virus-like particle formation.

Pancreas disease (PD) and sleeping disease (SD) are important viral scourges in aquaculture of Atlantic salmon and rainbow trout. The etiological agent of PD and SD is salmonid alphavirus (SAV), an unusual member of the Togaviridae (genus Alphavirus). SAV replicates at lower temperatures in fish. Ou...

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Bibliographic Details
Main Authors: Stefan W Metz, Femke Feenstra, Stephane Villoing, Marielle C van Hulten, Jan W van Lent, Joseph Koumans, Just M Vlak, Gorben P Pijlman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3185042?pdf=render