Early Impairment of Paracrine and Phenotypic Features in Resident Cardiac Mesenchymal Stromal Cells after Thoracic Radiotherapy

Early Impairment of Paracrine and Phenotypic Features in Resident Cardiac Mesenchymal Stromal Cells after Thoracic Radiotherapy

Radiotherapy-induced cardiac toxicity and consequent diseases still represent potential severe late complications for many cancer survivors who undergo therapeutic thoracic irradiation. We aimed to assess the phenotypic and paracrine features of resident cardiac mesenchymal stromal cells (CMSCs) at...

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Bibliographic Details
Main Authors: Vittorio Picchio, Roberto Gaetani, Francesca Pagano, Yuriy Derevyanchuk, Olivia Pagliarosi, Erica Floris, Claudia Cozzolino, Giacomo Bernava, Antonella Bordin, Filipe Rocha, Ana Rita Simões Pereira, Augusto Ministro, Ana Teresa Pinto, Elena De Falco, Gianpaolo Serino, Diana Massai, Radia Tamarat, Maurizio Pesce, Susana Constantino Rosa Santos, Elisa Messina, Isotta Chimenti
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:International Journal of Molecular Sciences
Subjects:
cardiotoxicity
radiotherapy
radiation-induced cardiomyopathy
radiation-induced heart disease
cardiac fibrosis
cardiac stromal cells
Online Access:https://www.mdpi.com/1422-0067/25/5/2873

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https://www.mdpi.com/1422-0067/25/5/2873

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