Ultrasensitive and Multiplexed Protein Imaging with Cleavable Fluorescent Tyramide and Antibody Stripping

Ultrasensitive and Multiplexed Protein Imaging with Cleavable Fluorescent Tyramide and Antibody Stripping

Multiplexed single-cell analysis of proteins in their native cellular contexts holds great promise to reveal the composition, interaction and function of the distinct cell types in complex biological systems. However, the existing multiplexed protein imaging technologies are limited by their detecti...

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Bibliographic Details
Main Authors: Thai Pham, Christopher D. Nazaroff, Joshua Labaer, Jia Guo
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
immunofluorescence
immunohistochemistry
single-cell
in situ analysis
proteomics
expression heterogeneity
Online Access:https://www.mdpi.com/1422-0067/22/16/8644

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https://www.mdpi.com/1422-0067/22/16/8644

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