Antimicrobial activity, membrane interaction and structural features of short arginine-rich antimicrobial peptides

Antimicrobial activity, membrane interaction and structural features of short arginine-rich antimicrobial peptides

Antimicrobial activity of many AMPs can be improved by lysine-to-arginine substitution due to a more favourable interaction of arginine guanidinium moiety with bacterial membranes. In a previous work, the structural and functional characterization of an amphipathic antimicrobial peptide named RiLK1,...

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Bibliographic Details
Main Authors: Bruna Agrillo, Alessandra Porritiello, Lorena Gratino, Marco Balestrieri, Yolande Therese Proroga, Andrea Mancusi, Loredana Cozzi, Teresa Vicenza, Principia Dardano, Bruno Miranda, Pablo V. Escribá, Marta Gogliettino, Gianna Palmieri
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Microbiology
Subjects:
antimicrobial compound
cationic arginine-rich peptide
arginine
membrane interaction
spectroscopy
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1244325/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2023.1244325/full

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