Plasminogen Deficiency Significantly Reduces Vascular Wall Disease in a Murine Model of Type IIa Hypercholesterolemia

Plasminogen Deficiency Significantly Reduces Vascular Wall Disease in a Murine Model of Type IIa Hypercholesterolemia

The fibrinolytic system has been implicated in the genesis and progression of atherosclerosis. It has been reported that a plasminogen (Pg) deficiency (<i>Plg<sup>−/−</sup></i>) exacerbates the progression of atherosclerosis in <i>Apoe<sup>−/−</sup></i>...

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Bibliographic Details
Main Authors: Takayuki Iwaki, Tomohiro Arakawa, Mayra J. Sandoval-Cooper, Denise L. Smith, Deborah Donahue, Victoria A. Ploplis, Kazuo Umemura, Francis J. Castellino
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Biomedicines
Subjects:
LDL receptor
apobec-1
plasminogen
atherosclerosis
foam cells
Online Access:https://www.mdpi.com/2227-9059/9/12/1832

Internet

https://www.mdpi.com/2227-9059/9/12/1832

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