A biochemical, theoretical and immunohistochemical study comparing the therapeutic efficacy of curcumin and taurine on T-2 toxin induced hepatotoxicity in rats

A biochemical, theoretical and immunohistochemical study comparing the therapeutic efficacy of curcumin and taurine on T-2 toxin induced hepatotoxicity in rats

Introduction: Foodborne trichothecene T-2 Toxin, is a highly toxic metabolite produced by Fusarium species contaminating animal and human food, causing multiple organ failure and health hazards. T-2 toxins induce hepatotoxicity via oxidative stress causing hepatocytes cytotoxicity and genotoxicity....

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Main Authors: Maryam H. Al-Zahrani, Maha J. Balgoon, Nagwa M. El-Sawi, Fawzia A. Alshubaily, Ebtihaj J. Jambi, Sohair M. Khojah, Raghad S. Baljoon, Nuha A. Alkhattabi, Lina A. Baz, Asmaa A. Alharbi, Amira M. Ahmed, Ayat M. Abo elkhair, Mohamed Ismael, Sahar M. Gebril
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Molecular Biosciences
Subjects:
T-2 toxin
hepatotoxicity
fibrosis
DNA damage
apoptosis
curcumin
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1172403/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2023.1172403/full

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