Type II Collagen-Specific B Cells Induce Immune Tolerance in Th1-Skewed, Th2-Skewed, and Arthritis-Prone Strains of Mice

Type II Collagen-Specific B Cells Induce Immune Tolerance in Th1-Skewed, Th2-Skewed, and Arthritis-Prone Strains of Mice

Antigen-specific regulatory T cells play key immune suppressive roles in autoimmune disease models and regulate the peripheral tolerance achieved via anterior chamber-associated immune deviation (ACAID). Articular cartilage has type II collagen (CII), which is a potent autoantigen protein in arthrit...

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Bibliographic Details
Main Authors: Shukkur M. Farooq, Hossam M. Ashour
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cells
Subjects:
ACAID
peripheral tolerance
immune privilege
regulatory T cells
collagen type II
B cells
Online Access:https://www.mdpi.com/2073-4409/10/4/870

Internet

https://www.mdpi.com/2073-4409/10/4/870

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