Sex and Tamoxifen confound murine experimental studies in cardiovascular tissue engineering

Abstract Tissue engineered vascular grafts hold promise for the creation of functional blood vessels from biodegradable scaffolds. Because the precise mechanisms regulating this process are still under investigation, inducible genetic mouse models are an important and widely used research tool. Howe...

Full description

Bibliographic Details
Main Authors: Kevin M. Blum, Lauren C. Roby, Jacob C. Zbinden, Yu-Chun Chang, Gabriel J. M. Mirhaidari, James W. Reinhardt, Tai Yi, Jenny C. Barker, Christopher K. Breuer
Format: Article
Language:English
Published: Nature Portfolio 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-87006-3